Selection of Poly-α 2,8-Sialic Acid Mimotopes from a Random Phage Peptide Library and Analysis of Their Bioactivity

Phage-Displayed Random Peptide Library -Mediated Cytotoxicity Identified from a α A Peptidomimetic Antagonist of TNF-

Peptide mimotopes selected from a random peptide library for diagnosis of Epstein-Barr virus infection.

Epstein-Barr virus (EBV) is a ubiquitous, worldwide infectious agent that causes infectious mononucleosis, affecting >90% of the world's population. Currently, enzyme-linked immunosorbent assay, mostly with purified preparations of EBV cell extracts to capture immunoglobulin M (IgM) antibodies in patients' serum, is used for primary diagnosis. Our objective was to determine whether a small set ...

Mimotopes of the Vi antigen of Salmonella enterica serovar typhi identified from phage display peptide library.

The capsular polysaccharide Vi antigen (ViCPS) is an essential virulence factor and also a protective antigen of Salmonella enterica serovar Typhi. A random 12-mer phage-displayed peptide library was used to identify mimotopes (epitope analogues) of this antigen by panning against a ViCPS-specific monoclonal antibody (MAb) ATVi. Approximately 75% of the phage clones selected in the fourth round...

Mimotopes of heat shock proteins of Salmonella enterica serovar Typhi identified from phage-displayed peptide library.

BACKGROUND Heat shock proteins (HSPs) are known to be involved in the pathogenesis of Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever. The objective of this study was to apply a phage display library to identify mimotopes of two HSPs, HSP90 and DnaK in S. Typhi. METHODOLOGY A 12-mer random peptide library expressed on the surface of the filamentous phage, M1...

‏‎a phonological contrastive analysis of kurdish and english‎‏

deposite the different criticisms on contrastive analysis it has been proved that the results of it(when processed)can be usuful in a tefl environment,specially at the level of phonology.this study is an attempt to compare and contrast the sound systems of kurdish and english for pedagogical aims. the consonants,vowels,stress and intonation of the twolanguages are described by the same model-ta...